Comparing the impact of cumulative insulin resistance surrogates exposure on stroke: optimizing prevention strategies

Table 4 ROC analysis for IR surrogates and CumIR surrogates in predicting stroke

	AUC	95%CI low	95%CI upp	Best threshold	Specificity	Sensitivity
TyG index^*	0.5761	0.5458	0.6063	8.2810	0.2957	0.8242
TG/HDL-C ratio^*	0.5771	0.5474	0.6067	1.6682	0.3829	0.7406
MetS-IR^*	0.5925	0.5619	0.6231	38.1325	0.6768	0.4640
eGDR	0.6541	0.6246	0.6835	9.5555	0.5493	0.6945
CumTyG index^†	0.5772	0.5463	0.6081	26.5597	0.6784	0.4380
CumTG/HDL-C ratio^†	0.5815	0.5511	0.6118	8.5673	0.6411	0.4784
CumMetS-IR^†	0.5878	0.5571	0.6184	104.1542	0.5025	0.6311
CumeGDR	0.6706	0.6427	0.6984	23.7991	0.6553	0.6110

Abbreviations: ROC: receiver-operating characteristic curve; AUC: area under the ROC curve; CI: confidence interval; TyG: triglyceride-glucose; TG/HDL-C: triglyceride to high-density lipoprotein cholesterol; MetS-IR: metabolic score for insulin resistance; eGDR: estimated glucose disposal rate; CumTyG: cumulative triglyceride-glucose; CumMetS-IR: cumulative metabolic score for insulin resistance; CumTG/HDL-C: cumulative triglyceride to high-density lipoprotein cholesterol; CumeGDR: cumulative estimated glucose disposal rate; CumIR: cumulative insulin resistance
*P < 0.05 compared with eGDR (Delong test)
^†P < 0.05 compared with CumeGDR (Delong test)

ISSN: 1476-511X