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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Arachidonic acid is involved in high-salt diet-induced coronary remodeling through stimulation of the IRE1α/XBP1s/RUNX2/OPN signaling cascade

Fig. 4

Arachidonic acid (10 µM, 24 h) treatment decreased the contractility of coronary arteries in rats. Summary data showing the concentration-dependent contractile responses to (A) 60 mM K+, (B) increasing concentrations of U46619 (0.01, 0.03, 0.1, 0.3, and 1 µM), and (C) CaCl2 (1, 2.5, 5, and 10 mmol/L) after incubation with AA. The data are presented as the means ± SEMs, with n = 6. Statistical significance is indicated as *P < 0.05 and **P < 0.01 compared with the normal control group. Abbreviations: U46619, 9, 11-dideoxy-11a, 9a-epoxymetha-noprostaglandin; SEM, standard error of the mean

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Lipids in Health and Disease

ISSN: 1476-511X